Secretion management devices assist in safely removing respiratory secretions for patients with compromised cough reflexes or on mechanical ventilation. Key tools include mechanical insufflation-exsufflation (MI-E) devices, which simulate coughing, and suction pumps or closed suction systems for manual or ventilated secretion removal. These devices maintain airway patency, prevent complications like pneumonia, and improve respiratory function, particularly for patients with neuromuscular disorders or chronic respiratory conditions. Designed for safety and infection control, they are essential in critical care and long-term respiratory management.